The immune-system protects our organism from agression by pathogens and cancer. However, immune-responses need to be carefully restrained to avoid "immune-pathology" such as autoimmune disease (e.g. type I diabetes, rheumatoid arthritis), allergy, and chronic inflammation (e.g. inflammatory bowel diseases)


Our immunology-team works on the molecular and cellular mechanisms that control immune responses. We thus contribute to the development of innovative therapies against immune-pathology. We also use our findings to develop an innovating experimental cellular immunotherapy against chronic graft-rejection

Development of immune-tolerance

Immune-tolerance mainly develops in the thymus. We investigate the molecular and cellular mechanisms involved

Prevention of graft rejection

We investigate the potential of natural immune tolerance to prevent rejection of transplanted organs and tissues

Our epigenetic studies

The development and function of immune- cells are controlled by epigenetic mechanisms, which we investigate